From UC Davis:
Patients who overdose on opioids and have a pulse are often given naloxone (Narcan) by first responders, a common life-saving measure.
However, emergency medical service (EMS) agencies have different protocols for administering naloxone, so there is little evidence to support its use in patients without a pulse who experienced opioid-associated out of hospital cardiac arrest (OHCA).
A recent study by UC Davis Health researchers set out to assess the effects of giving naloxone administration by paramedics to patients with OHCA.
The study, published in Jama Open Network, concluded there was an association between naloxone administration, and both return of spontaneous circulation and survival to hospital discharge.
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