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IO Access Location

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Reference: Tanner et al, A retrospective comparison of upper and lower extremity intraosseous access during out-of-hospital cardiac arrest resuscitation. Prehospital Emergency Care. February 2024.


  • Population: Adults 18 or greater with an OOHCA

  • Excluded: IV access before IO, DNR, interfacility transfers, and EMS-witnessed arrests

  • Intervention: Upper extremity IO placement (100% humeral)

  • Comparison: Lower extremity IO placement (97.8% tibial & 2.3% femoral)

  • Outcome:

  • Primary Outcome: Return of spontaneous circulation (ROSC)

  • Secondary Outcomes: Survival to hospital discharge and survival to discharge home.

Authors’ Conclusions: In this large prehospital dataset, upper extremity IO access was associated with a small increase in the odds of ROSC in comparison to lower extremity IO access. These data support the need for prospective investigation of the ideal IO access site during OHCA resuscitation.

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