Re-DOSE VF… DSED for Shock-Refractory VF?

From Journal Feed:

Spoon Feed

This secondary analysis of the DOSE VF trial found that DSED (dual sequence external defibrillation) was the superior strategy for obtaining ROSC and functional neurologic outcome regardless of whether the patient was in recurrent VF or shock-refractory VF after three standard defibrillation shocks.

DSED was found to be superior to standard defibrillation for survival overall and specifically for the shock-refractory group; no patient in shock refractory VF survived to hospital discharge using standard defibrillation. DSED was also superior to standard defibrillation for ROSC and neurologic survival for both sub-groups. Vector change defibrillation was not found to be superior to standard defibrillation overall or in either of the subgroups for survival.

Source

The impact of alternate defibrillation strategies on shock-refractory and recurrent ventricular fibrillation: A secondary analysis of the DOSE VF cluster randomized controlled trial. Resuscitation. 2024 May;198:110186. doi: 10.1016/j.resuscitation.2024.110186. Epub 2024 Mar 24. PMID: 38522736.